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Comparison of dimension reduction-based logistic regression models for case-control genome-wide association study: principal components analysis vs. partial least squares

With recent advances in biotechnology, genome-wide association study (GWAS) has been widely used to identify genetic variants that underlie human complex diseases and traits. In case-control GWAS, typical statistical strategy is traditional logistical regression (LR) based on single-locus analysis....

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Detalles Bibliográficos
Autores principales: Yi, Honggang, Wo, Hongmei, Zhao, Yang, Zhang, Ruyang, Dai, Junchen, Jin, Guangfu, Ma, Hongxia, Wu, Tangchun, Hu, Zhibin, Lin, Dongxin, Shen, Hongbing, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547378/
https://www.ncbi.nlm.nih.gov/pubmed/26243516
http://dx.doi.org/10.7555/JBR.29.20140043