Investigation of Inhibition Mechanism of Chemokine Receptor CCR5 by Micro-second Molecular Dynamics Simulations

Chemokine receptor 5 (CCR5) belongs to G protein coupled receptors (GPCRs) and plays an important role in treatment of human immunodeficiency virus (HIV) infection since HIV uses CCR5 protein as a co-receptor. Recently, the crystal structure of CCR5-bound complex with an approved anti-retroviral dru...

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Detalles Bibliográficos
Autores principales: Salmas, Ramin Ekhteiari, Yurtsever, Mine, Durdagi, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547396/
https://www.ncbi.nlm.nih.gov/pubmed/26299310
http://dx.doi.org/10.1038/srep13180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547396/
https://www.ncbi.nlm.nih.gov/pubmed/26299310
http://dx.doi.org/10.1038/srep13180

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