Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

A subset of nuclear receptors (NRs) function as obligate heterodimers with retinoid X receptor (RXR), allowing integration of ligand-dependent signals across the dimer interface via an unknown structural mechanism. Using nuclear magnetic resonance (NMR) spectroscopy, x-ray crystallography and hydrog...

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Detalles Bibliográficos
Autores principales: Kojetin, Douglas J., Matta-Camacho, Edna, Hughes, Travis S., Srinivasan, Sathish, Nwachukwu, Jerome C., Cavett, Valerie, Nowak, Jason, Chalmers, Michael J., Marciano, David P., Kamenecka, Theodore M., Shulman, Andrew I., Rance, Mark, Griffin, Patrick R., Bruning, John B., Nettles, Kendall W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547401/
https://www.ncbi.nlm.nih.gov/pubmed/26289479
http://dx.doi.org/10.1038/ncomms9013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547401/
https://www.ncbi.nlm.nih.gov/pubmed/26289479
http://dx.doi.org/10.1038/ncomms9013

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