Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer()

Non–small cell lung cancer (NSCLC) patients have very low survival rates because the current therapeutic strategies are not fully effective. Although EGFR tyrosine kinase inhibitors are effective for NSCLC patients harboring EGFR mutations, patients invariably develop resistance to these agents. Alt...

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Detalles Bibliográficos
Autores principales: Bora-Singhal, Namrata, Perumal, Deepak, Nguyen, Jonathan, Chellappan, Srikumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547412/
https://www.ncbi.nlm.nih.gov/pubmed/26297432
http://dx.doi.org/10.1016/j.neo.2015.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547412/
https://www.ncbi.nlm.nih.gov/pubmed/26297432
http://dx.doi.org/10.1016/j.neo.2015.07.001

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