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Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells

BACKGROUND: microRNA-122 (miR-122) is the most abundant and specific miRNA in the liver. It acts as an important tumor suppressor in hepatocellular carcinoma (HCC) through regulating its target genes, but details of its own regulation are largely unknown. Farnesoid X receptor (FXR), a transcription...

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Detalles Bibliográficos
Autores principales: He, Jialin, Zhao, Kai, Zheng, Lu, Xu, Zhizhen, Gong, Wei, Chen, Shan, Shen, Xiaodong, Huang, Gang, Gao, Min, Zeng, Yijun, Zhang, Yan, He, Fengtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547435/
https://www.ncbi.nlm.nih.gov/pubmed/26302777
http://dx.doi.org/10.1186/s12943-015-0427-9