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Direct and Propagated Effects of Small Molecules on Protein–Protein Interaction Networks

Networks of protein–protein interactions (PPIs) link all aspects of cellular biology. Dysfunction in the assembly or dynamics of PPI networks is a hallmark of human disease, and as such, there is growing interest in the discovery of small molecules that either promote or inhibit PPIs. PPIs were once...

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Detalles Bibliográficos
Autores principales: Cesa, Laura C., Mapp, Anna K., Gestwicki, Jason E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547496/
https://www.ncbi.nlm.nih.gov/pubmed/26380257
http://dx.doi.org/10.3389/fbioe.2015.00119