Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis

Natural product curcumin (Cur) and H(2)S-releasing prodrug SH-aspirin (SH-ASA) are potential anticancer agents with diverse mechanisms, but their clinical application prospects are restricted by hydrophobicity and limited efficiency. In this work, we coencapsulated SH-ASA and Cur into methoxy poly(e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Lin, Duan, Xingmei, Zeng, Shi, Men, Ke, Zhang, Xueyan, Yang, Li, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547632/
https://www.ncbi.nlm.nih.gov/pubmed/26316750
http://dx.doi.org/10.2147/IJN.S84326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547632/
https://www.ncbi.nlm.nih.gov/pubmed/26316750
http://dx.doi.org/10.2147/IJN.S84326

Ejemplares similares