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Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis

Natural product curcumin (Cur) and H(2)S-releasing prodrug SH-aspirin (SH-ASA) are potential anticancer agents with diverse mechanisms, but their clinical application prospects are restricted by hydrophobicity and limited efficiency. In this work, we coencapsulated SH-ASA and Cur into methoxy poly(e...

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Detalles Bibliográficos
Autores principales:	Zhou, Lin, Duan, Xingmei, Zeng, Shi, Men, Ke, Zhang, Xueyan, Yang, Li, Li, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547632/ https://www.ncbi.nlm.nih.gov/pubmed/26316750 http://dx.doi.org/10.2147/IJN.S84326

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