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An ex vivo RT-qPCR-based assay for human peripheral leukocyte responsiveness to glucocorticoids in surgically induced inflammation

INTRODUCTION: An assay to determine glucocorticoid (GC) responsiveness in humans could be used to monitor GC non-responsiveness in states of GC insufficiency and could provide a tool to adapt GC treatment to individual patients. We propose an ex vivo assay to test GC responsiveness in peripheral leu...

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Detalles Bibliográficos
Autores principales: Gråberg, Truls, Strömmer, Lovisa, Hedman, Erik, Uzunel, Mehmet, Ehrenborg, Ewa, Wikström, Ann-Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547639/
https://www.ncbi.nlm.nih.gov/pubmed/26316794
http://dx.doi.org/10.2147/JIR.S84165