The Presence of HLA-E-Restricted, CMV-Specific CD8(+) T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection

The human cytomegalovirus (CMV) immune evasion protein, UL40, shares an identical peptide sequence with that found in the leader sequence of many human leukocyte antigen (HLA)-C alleles and when complexed with HLA-E, can modulate NK cell functions via interactions with the CD94-NKG2 receptors. Howev...

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Detalles Bibliográficos
Autores principales: Sullivan, Lucy C., Westall, Glen P., Widjaja, Jacqueline M. L., Mifsud, Nicole A., Nguyen, Thi H. O., Meehan, Aislin C., Kotsimbos, Tom C., Brooks, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547726/
https://www.ncbi.nlm.nih.gov/pubmed/26302084
http://dx.doi.org/10.1371/journal.pone.0135972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547726/
https://www.ncbi.nlm.nih.gov/pubmed/26302084
http://dx.doi.org/10.1371/journal.pone.0135972

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