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The Presence of HLA-E-Restricted, CMV-Specific CD8(+) T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection
The human cytomegalovirus (CMV) immune evasion protein, UL40, shares an identical peptide sequence with that found in the leader sequence of many human leukocyte antigen (HLA)-C alleles and when complexed with HLA-E, can modulate NK cell functions via interactions with the CD94-NKG2 receptors. Howev...
Autores principales: | Sullivan, Lucy C., Westall, Glen P., Widjaja, Jacqueline M. L., Mifsud, Nicole A., Nguyen, Thi H. O., Meehan, Aislin C., Kotsimbos, Tom C., Brooks, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547726/ https://www.ncbi.nlm.nih.gov/pubmed/26302084 http://dx.doi.org/10.1371/journal.pone.0135972 |
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