Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation

Liver grafts donated after cardiac death are increasingly used to expand the donor pool but are prone to ischaemic-type biliary lesions. The anti-inflammatory effects of the activated pregnane X receptor have previously been shown to be beneficial in a number of inflammatory liver conditions. Howeve...

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Detalles Bibliográficos
Autores principales: Amer, Aimen O., Probert, Philip M., Dunn, Michael, Knight, Margaret, Vallance, Abigail E., Flecknell, Paul A., Oakley, Fiona, Cameron, Iain, White, Steven A., Blain, Peter G., Wright, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547732/
https://www.ncbi.nlm.nih.gov/pubmed/26302150
http://dx.doi.org/10.1371/journal.pone.0136173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547732/
https://www.ncbi.nlm.nih.gov/pubmed/26302150
http://dx.doi.org/10.1371/journal.pone.0136173

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