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Analysis of the Contrasting Pathogenicities Induced by the D222G Mutation in 1918 and 2009 Pandemic Influenza A Viruses

[Image: see text] In 2009, the D222G mutation in the hemagglutinin (HA) glycoprotein of pandemic H1N1 influenza A virus was found to correlate with fatal and severe human infections. Previous static structural analysis suggested that, unlike the H1N1 viruses prevalent in 1918, the mutation did not c...

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Detalles Bibliográficos
Autores principales: Shang, Cheng, Whittleston, Chris S., Sutherland-Cash, Kyle H., Wales, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547735/
https://www.ncbi.nlm.nih.gov/pubmed/26321885
http://dx.doi.org/10.1021/ct5010565