Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model

Dengue virus is a major global health threat and can lead to life-threatening hemorrhagic complications due to immune activation and cytokine production. Cross-reactive antibodies to an earlier dengue virus infection are a recognized risk factor for severe disease. These antibodies bind heterologous...

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Detalles Bibliográficos
Autores principales: Callaway, Justin B., Smith, Scott A., Widman, Douglas G., McKinnon, Karen P., Scholle, Frank, Sempowski, Gregory D., Dittmer, Dirk P., Crowe, James E., de Silva, Aravinda M., Ting, Jenny P.-Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547738/
https://www.ncbi.nlm.nih.gov/pubmed/26301593
http://dx.doi.org/10.1371/journal.pone.0136708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547738/
https://www.ncbi.nlm.nih.gov/pubmed/26301593
http://dx.doi.org/10.1371/journal.pone.0136708

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