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Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases

Recent advances in genome sequencing techniques have improved our understanding of the genotype-phenotype relationship between genetic variants and human diseases. However, genetic variations uncovered from patient populations do not provide enough information to understand the mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Han, Seong Kyu, Kim, Inhae, Hwang, Jihye, Kim, Sanguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547739/
https://www.ncbi.nlm.nih.gov/pubmed/26301634
http://dx.doi.org/10.1371/journal.pone.0136300