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Human insulin polymorphism upon ligand binding and pH variation: the case of 4-ethylresorcinol

This study focuses on the effects of the organic ligand 4-ethylresorcinol on the crystal structure of human insulin using powder X-ray crystallography. For this purpose, systematic crystallization experiments have been conducted in the presence of the organic ligand and zinc ions within the pH range...

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Detalles Bibliográficos
Autores principales: Fili, S., Valmas, A., Norrman, M., Schluckebier, G., Beckers, D., Degen, T., Wright, J., Fitch, A., Gozzo, F., Giannopoulou, A. E., Karavassili, F., Margiolaki, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547821/
https://www.ncbi.nlm.nih.gov/pubmed/26306195
http://dx.doi.org/10.1107/S2052252515013159