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Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud

Parameter optimization coupled with model selection is a convenient approach to infer gene regulatory networks from experimental gene expression data, but so far it has been limited to single cells or static tissues where growth is not significant. Here, we present a computational study in which we...

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Detalles Bibliográficos
Autores principales: Uzkudun, Manu, Marcon, Luciano, Sharpe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547844/
https://www.ncbi.nlm.nih.gov/pubmed/26174932
http://dx.doi.org/10.15252/msb.20145882