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Extensive mapping of an innate immune network with CRISPR

The application of the CRISPR-Cas9 system marks a major breakthrough for genetic screens, particularly in mammalian cells where high-throughput targeted gene editing has been lacking. Parnas et al (2015) apply this screening technology to mouse bone marrow-derived dendritic cells in order to study t...

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Detalles Bibliográficos
Autores principales: Aregger, Michael, Hart, Traver, Moffat, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547849/
https://www.ncbi.nlm.nih.gov/pubmed/26208794
http://dx.doi.org/10.15252/msb.20156373