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Structure of silent transcription intervals and noise characteristics of mammalian genes
Mammalian transcription occurs stochastically in short bursts interspersed by silent intervals showing a refractory period. However, the underlying processes and consequences on fluctuations in gene products are poorly understood. Here, we use single allele time-lapse recordings in mouse cells to id...
Autores principales: | Zoller, Benjamin, Nicolas, Damien, Molina, Nacho, Naef, Felix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547851/ https://www.ncbi.nlm.nih.gov/pubmed/26215071 http://dx.doi.org/10.15252/msb.20156257 |
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