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Cancer type-dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types
Cancers, like many diseases, are normally caused by combinations of genetic alterations rather than by changes affecting single genes. It is well established that the genetic alterations that drive cancer often interact epistatically, having greater or weaker consequences in combination than expecte...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547852/ https://www.ncbi.nlm.nih.gov/pubmed/26227665 http://dx.doi.org/10.15252/msb.20156102 |