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Anesthetic and pathological changes following high doses of ketamine and xylazine in Sprague Dawley rats

The main objective of this study was to compare the effects of ketamine and xylazine in aging rats when coadministered intraperitoneally at high anesthetic doses. Three groups (n=6 rats/group) consisting of rats at 3, 6 and 12 months of age were used. During anesthesia, animals were monitored for he...

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Detalles Bibliográficos
Autores principales: GIROUX, Marie-Chantal, HÉLIE, Pierre, BURNS, Patrick, VACHON, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547998/
https://www.ncbi.nlm.nih.gov/pubmed/25818316
http://dx.doi.org/10.1538/expanim.14-0088