A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation

A general radioprotective effect by fibroblast growth factor (FGF) has been extensively described since the early 1990s; however, the molecular mechanisms involved remain largely unknown. Radiation-induced DNA double-strand breaks (DSBs) lead to a complex set of responses in eukaryotic cells. One of...

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Detalles Bibliográficos
Autores principales: Benzina, Sami, Pitaval, Amandine, Lemercier, Claudie, Lustremant, Celine, Frouin, Vincent, Wu, Ning, Papine, Alexandre, Soussaline, Françoise, Romeo, Paul-Henri, Gidrol, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548013/
https://www.ncbi.nlm.nih.gov/pubmed/25894690
http://dx.doi.org/10.1007/s00018-015-1901-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548013/
https://www.ncbi.nlm.nih.gov/pubmed/25894690
http://dx.doi.org/10.1007/s00018-015-1901-7

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