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A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation
A general radioprotective effect by fibroblast growth factor (FGF) has been extensively described since the early 1990s; however, the molecular mechanisms involved remain largely unknown. Radiation-induced DNA double-strand breaks (DSBs) lead to a complex set of responses in eukaryotic cells. One of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Basel
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548013/ https://www.ncbi.nlm.nih.gov/pubmed/25894690 http://dx.doi.org/10.1007/s00018-015-1901-7 |