Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice

Background: Mutations in WFS1 gene cause Wolfram syndrome, which is a rare autosomal recessive disorder, characterized by diabetes insipidus, diabetes mellitus, optic nerve atrophy, and deafness. The WFS1 gene product wolframin is located in the endoplasmic reticulum. Mice lacking this gene exhibit...

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Detalles Bibliográficos
Autores principales: Tein, Karin, Kasvandik, Sergo, Kõks, Sulev, Vasar, Eero, Terasmaa, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548212/
https://www.ncbi.nlm.nih.gov/pubmed/26379490
http://dx.doi.org/10.3389/fnmol.2015.00045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548212/
https://www.ncbi.nlm.nih.gov/pubmed/26379490
http://dx.doi.org/10.3389/fnmol.2015.00045

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