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Thyroid-Stimulating Hormone Increases HNF-4α Phosphorylation via cAMP/PKA Pathway in the Liver

Hepatocyte nuclear factor-4 alpha (HNF-4α) is an orphan nuclear receptor with important roles in hepatic metabolism. Protein phosphorylation plays a functional role in its nuclear localization, DNA binding, and transactivation. Thyroid-stimulating hormone (TSH) is a hormone produced by the anterior...

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Detalles Bibliográficos
Autores principales: Song, Yongfeng, Zheng, Dongmei, Zhao, Meng, Qin, Yejun, Wang, Tingting, Xing, Wanjia, Gao, Ling, Zhao, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548215/
https://www.ncbi.nlm.nih.gov/pubmed/26302721
http://dx.doi.org/10.1038/srep13409