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Thyroid-Stimulating Hormone Increases HNF-4α Phosphorylation via cAMP/PKA Pathway in the Liver

Hepatocyte nuclear factor-4 alpha (HNF-4α) is an orphan nuclear receptor with important roles in hepatic metabolism. Protein phosphorylation plays a functional role in its nuclear localization, DNA binding, and transactivation. Thyroid-stimulating hormone (TSH) is a hormone produced by the anterior...

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Detalles Bibliográficos
Autores principales:	Song, Yongfeng, Zheng, Dongmei, Zhao, Meng, Qin, Yejun, Wang, Tingting, Xing, Wanjia, Gao, Ling, Zhao, Jiajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548215/ https://www.ncbi.nlm.nih.gov/pubmed/26302721 http://dx.doi.org/10.1038/srep13409

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