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Selective enrichment of mycobacterial proteins from infected host macrophages

Upon infection, Mycobacterium tuberculosis (Mtb) deploys specialized secretion machinery to deliver virulent proteins with the capacity to modulate a variety of host-cellular pathways. Studies on the identification of intra-macrophage Mtb proteins, however, are constricted by an inability to selecti...

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Detalles Bibliográficos
Autores principales: Chande, Ajit G., Siddiqui, Zaved, Midha, Mukul Kumar, Sirohi, Varsha, Ravichandran, Srikanth, Rao, Kanury V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548221/
https://www.ncbi.nlm.nih.gov/pubmed/26303024
http://dx.doi.org/10.1038/srep13430