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Histone demethylase JMJD3 is required for osteoblast differentiation in mice

JMJD3 (KDM6B) is an H3K27me3 demethylases and emerges as an important player in developmental processes. Although some evidence indicated the involvement of JMJD3 in osteoblast differentiation in vitro, its role as a whole in osteoblast differentiation and bone formation in vivo remains unknown. Her...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Xu, Longyong, Xu, Longxia, Xu, Qing, Karsenty, Gerard, Chen, Charlie Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548232/
https://www.ncbi.nlm.nih.gov/pubmed/26302868
http://dx.doi.org/10.1038/srep13418