Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo

Microvesicles shed from cells carry constituents of the cell cytoplasm, including, of importance in multidrug resistance to cancer chemotherapy, drugs that the tumor cell attempts to efflux. To see whether such drugs could be used at lower concentrations with the same efficacy, it was first shown th...

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Detalles Bibliográficos
Autores principales: Jorfi, Samireh, Ansa-Addo, Ephraim A., Kholia, Sharad, Stratton, Dan, Valley, Shaunelle, Lange, Sigrun, Inal, Jameel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548233/
https://www.ncbi.nlm.nih.gov/pubmed/26302712
http://dx.doi.org/10.1038/srep13006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548233/
https://www.ncbi.nlm.nih.gov/pubmed/26302712
http://dx.doi.org/10.1038/srep13006

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