Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase

Soluble epoxide hydrolase (sEH) has C-terminal epoxide hydrolase and N-terminal lipid phosphatase activity. Its hydrolase activity is associated with endothelial nitric oxide synthase (eNOS) dysfunction. However, little is known about the role of sEH phosphatase in regulating eNOS activity. Simvasta...

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Detalles Bibliográficos
Autores principales: Hou, Hsin-Han, Liao, Yi-Jen, Hsiao, Sheng-Huang, Shyue, Song-Kun, Lee, Tzong-Shyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548251/
https://www.ncbi.nlm.nih.gov/pubmed/26304753
http://dx.doi.org/10.1038/srep13524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548251/
https://www.ncbi.nlm.nih.gov/pubmed/26304753
http://dx.doi.org/10.1038/srep13524

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