UCP-3 uncoupling protein confers hypoxia resistance to renal epithelial cells and is upregulated in renal cell carcinoma

Tumor cells can adapt to a hostile environment with reduced oxygen supply. The present study aimed to identify mechanisms that confer hypoxia resistance. Partially hypoxia/reoxygenation (H/R)-resistant proximal tubular (PT) cells were selected by exposing PT cultures to repetitive cycles of H/R. The...

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Detalles Bibliográficos
Autores principales: Braun, Norbert, Klumpp, Dominik, Hennenlotter, Jörg, Bedke, Jens, Duranton, Christophe, Bleif, Martin, Huber, Stephan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548255/
https://www.ncbi.nlm.nih.gov/pubmed/26304588
http://dx.doi.org/10.1038/srep13450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548255/
https://www.ncbi.nlm.nih.gov/pubmed/26304588
http://dx.doi.org/10.1038/srep13450

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