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HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma

Previous studies indicated a role of hepatocellular carcinoma-related protein-1(HCRP-1) in human cancers, however, its expression pattern in renal cell carcinoma (RCC) and the molecular mechanism of HCRP-1 on cancer progression have not been characterized. In the present study, HCRP-1 expression was...

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Detalles Bibliográficos
Autores principales: Chen, Feifei, Deng, Junpeng, Liu, Xin, Li, Wang, Zheng, Junnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548257/
https://www.ncbi.nlm.nih.gov/pubmed/26304749
http://dx.doi.org/10.1038/srep13470