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Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α–Dependent Senescence-Associated Secretory Phenotype

Vascular smooth muscle cells (VSMCs) that become senescent are both present within atherosclerotic plaques and thought to be important to the disease process. However, senescent VSMCs are generally considered to only contribute through inaction, with failure to proliferate resulting in VSMC- and col...

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Detalles Bibliográficos
Autores principales: Gardner, Sarah E., Humphry, Melanie, Bennett, Martin R., Clarke, Murray C.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548545/
https://www.ncbi.nlm.nih.gov/pubmed/26139463
http://dx.doi.org/10.1161/ATVBAHA.115.305896