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D-α-tocopherol polyethylene glycol succinate-based derivative nanoparticles as a novel carrier for paclitaxel delivery

Paclitaxel (PTX) is one of the most effective antineoplastic drugs. Its current clinical administration Taxol(®) is formulated in Cremophor EL, which causes serious side effects. Nanoparticles (NP) with lower systemic toxicity and enhanced therapeutic efficiency may be an alternative formulation of...

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Detalles Bibliográficos
Autores principales: Wu, Yupei, Chu, Qian, Tan, Songwei, Zhuang, Xiangting, Bao, Yuling, Wu, Tingting, Zhang, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548758/
https://www.ncbi.nlm.nih.gov/pubmed/26316751
http://dx.doi.org/10.2147/IJN.S82847