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Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer
BACKGROUND: NK cells can destroy tumor cells without prior sensitization or immunization. Tumors often lose expression of MHC molecules and/or antigens. However, NK cells can lyse tumor cells in a non-MHC-restricted manner and independent of the expression of tumor-associated antigens. NK cells are...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548900/ https://www.ncbi.nlm.nih.gov/pubmed/26303618 http://dx.doi.org/10.1186/s12967-015-0632-8 |