Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer

BACKGROUND: NK cells can destroy tumor cells without prior sensitization or immunization. Tumors often lose expression of MHC molecules and/or antigens. However, NK cells can lyse tumor cells in a non-MHC-restricted manner and independent of the expression of tumor-associated antigens. NK cells are...

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Detalles Bibliográficos
Autores principales: Sakamoto, Naoyuki, Ishikawa, Takeshi, Kokura, Satoshi, Okayama, Tetsuya, Oka, Kaname, Ideno, Mitsuko, Sakai, Fumiyo, Kato, Akiko, Tanabe, Masashige, Enoki, Tatsuji, Mineno, Junichi, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548900/
https://www.ncbi.nlm.nih.gov/pubmed/26303618
http://dx.doi.org/10.1186/s12967-015-0632-8

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