The antiepileptic drug levetiracetam improves auditory gating in DBA/2 mice

Schizophrenia is associated with deficits in P50 gating. This deficit is preclinically modeled in the DBA/2 mouse by depth recordings in the hippocampus. Neurobiologically, the deficit may be due to dysfunction in inhibitory circuitry. It follows that anti-epileptic drugs which impact this circuitry...

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Detalles Bibliográficos
Autores principales: Smucny, Jason, Stevens, Karen E, Tregellas, Jason R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548960/
https://www.ncbi.nlm.nih.gov/pubmed/26317115
http://dx.doi.org/10.1038/npjschz.2015.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548960/
https://www.ncbi.nlm.nih.gov/pubmed/26317115
http://dx.doi.org/10.1038/npjschz.2015.2

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