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The antiepileptic drug levetiracetam improves auditory gating in DBA/2 mice
Schizophrenia is associated with deficits in P50 gating. This deficit is preclinically modeled in the DBA/2 mouse by depth recordings in the hippocampus. Neurobiologically, the deficit may be due to dysfunction in inhibitory circuitry. It follows that anti-epileptic drugs which impact this circuitry...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548960/ https://www.ncbi.nlm.nih.gov/pubmed/26317115 http://dx.doi.org/10.1038/npjschz.2015.2 |