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Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice

Fas (CD95) is a member of the TNF-receptor family expressed on a wide range of cells. Interaction of Fas with its receptor, Fas ligand (Fas-L), stimulates an intracellular cascade of events that leads to apoptosis. Because apoptosis of inflammatory cells plays a key role in atherosclerosis we sought...

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Detalles Bibliográficos
Autores principales: Kubo, Nobuhiko, McCurdy, Sara, Boisvert, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Applied Systems srl 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548988/
https://www.ncbi.nlm.nih.gov/pubmed/26322329
http://dx.doi.org/10.15190/d.2015.29