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Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice
Fas (CD95) is a member of the TNF-receptor family expressed on a wide range of cells. Interaction of Fas with its receptor, Fas ligand (Fas-L), stimulates an intracellular cascade of events that leads to apoptosis. Because apoptosis of inflammatory cells plays a key role in atherosclerosis we sought...
Autores principales: | Kubo, Nobuhiko, McCurdy, Sara, Boisvert, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Applied Systems srl
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548988/ https://www.ncbi.nlm.nih.gov/pubmed/26322329 http://dx.doi.org/10.15190/d.2015.29 |
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