High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss

Mitochondrial dysfunction plays an important role in obesity-induced cardiac impairment. SIRT3 is a mitochondrial protein associated with increased human life span and metabolism. This study investigated the functional role of SIRT3 in obesity-induced cardiac dysfunction. Wild-type (WT) and SIRT3 kn...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Heng, Vaka, Venkata Ramana, He, Xiaochen, Booz, George W, Chen, Jian-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549035/
https://www.ncbi.nlm.nih.gov/pubmed/25782072
http://dx.doi.org/10.1111/jcmm.12556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549035/
https://www.ncbi.nlm.nih.gov/pubmed/25782072
http://dx.doi.org/10.1111/jcmm.12556

Ejemplares similares