Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner

Vascular endothelial cell (VEC) senescence is considered an early event in the development of atherosclerotic lesions. Stressful stimuli, in particular oxidative stress, have been linked to premature senescence in the vasculature. Foam cells are a major source of reactive oxygen species and may play...

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Detalles Bibliográficos
Autores principales: Riahi, Yael, Kaiser, Nurit, Cohen, Guy, Abd-Elrahman, Ihab, Blum, Galia, Shapira, Oz M, Koler, Tomer, Simionescu, Maya, Sima, Anca V, Zarkovic, Neven, Zarkovic, Kamelija, Orioli, Marica, Aldini, Giancarlo, Cerasi, Erol, Leibowitz, Gil, Sasson, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549039/
https://www.ncbi.nlm.nih.gov/pubmed/25754218
http://dx.doi.org/10.1111/jcmm.12561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549039/
https://www.ncbi.nlm.nih.gov/pubmed/25754218
http://dx.doi.org/10.1111/jcmm.12561

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