Acacetin inhibits expression of matrix metalloproteinases via a MAPK-dependent mechanism in fibroblast-like synoviocytes

It is well known that rheumatoid arthritis (RA) is an autoimmune joint disease in which fibroblast-like synoviocytes (FLSs) play a pivotal role. In this study, we investigated the anti-arthritic properties of acacetin in FLSs. The expression of matrix metalloproteinase (MMP)-1, MMP-3 and MMP-13 were...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Ping, Yang, Zhi-Gao, Hu, Peng-Fei, Bao, Jia-Peng, Wu, Li-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549041/
https://www.ncbi.nlm.nih.gov/pubmed/25856795
http://dx.doi.org/10.1111/jcmm.12564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549041/
https://www.ncbi.nlm.nih.gov/pubmed/25856795
http://dx.doi.org/10.1111/jcmm.12564

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