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Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome

Paclitaxel is generally used to treat cancers in clinic as an inhibitor of cell division. However, the acquired resistance in tumours limits its clinical efficacy. Therefore, the aim of this study was to detect whether co-treatment with lentinan enhanced the anti-cancer effects of paclitaxel in A549...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Gu, Jun, Qi, Jun, Zeng, Xiao-Ning, Ji, Juan, Chen, Zheng-Zhen, Sun, Xiu-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549045/
https://www.ncbi.nlm.nih.gov/pubmed/25858687
http://dx.doi.org/10.1111/jcmm.12570