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Endogenous Opioid-Masked Latent Pain Sensitization: Studies from Mouse to Human

Following the resolution of a severe inflammatory injury in rodents, administration of mu-opioid receptor inverse agonists leads to reinstatement of pain hypersensitivity. The mechanisms underlying this form of latent pain sensitization (LS) likely contribute to the development of chronic pain, but...

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Detalles Bibliográficos
Autores principales: Pereira, Manuel P., Donahue, Renee R., Dahl, Jørgen B., Werner, Marianne, Taylor, Bradley K., Werner, Mads U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549112/
https://www.ncbi.nlm.nih.gov/pubmed/26305798
http://dx.doi.org/10.1371/journal.pone.0134441