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Endogenous Opioid-Masked Latent Pain Sensitization: Studies from Mouse to Human
Following the resolution of a severe inflammatory injury in rodents, administration of mu-opioid receptor inverse agonists leads to reinstatement of pain hypersensitivity. The mechanisms underlying this form of latent pain sensitization (LS) likely contribute to the development of chronic pain, but...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549112/ https://www.ncbi.nlm.nih.gov/pubmed/26305798 http://dx.doi.org/10.1371/journal.pone.0134441 |