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Identification of the Lomofungin Biosynthesis Gene Cluster and Associated Flavin-Dependent Monooxygenase Gene in Streptomyces lomondensis S015

Streptomyces lomondensis S015 synthesizes the broad-spectrum phenazine antibiotic lomofungin. Whole genome sequencing of this strain revealed a genomic locus consisting of 23 open reading frames that includes the core phenazine biosynthesis gene cluster lphzGFEDCB. lomo10, encoding a putative flavin...

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Detalles Bibliográficos
Autores principales: Zhang, Chunxiao, Sheng, Chaolan, Wang, Wei, Hu, Hongbo, Peng, Huasong, Zhang, Xuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549113/
https://www.ncbi.nlm.nih.gov/pubmed/26305803
http://dx.doi.org/10.1371/journal.pone.0136228