Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine

BACKGROUND: The gain-of-function mutation of the RET proto-oncogene, which encodes a receptor tyrosine kinase, is strongly associated with the development of several medullary thyroid carcinomas (MTCs). Thus, the RET protein has been explored as an excellent target for progressive and advanced MTC....

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Detalles Bibliográficos
Autores principales: Kumarasamy, Vishnu Muthuraj, Shin, Yoon-Joo, White, John, Sun, Daekyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549123/
https://www.ncbi.nlm.nih.gov/pubmed/26307103
http://dx.doi.org/10.1186/s12885-015-1610-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549123/
https://www.ncbi.nlm.nih.gov/pubmed/26307103
http://dx.doi.org/10.1186/s12885-015-1610-5

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