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Functional contributions of glutamate transporters at the parallel fibre to Purkinje neuron synapse–relevance for the progression of cerebellar ataxia

BACKGROUND: Rapid uptake of glutamate by neuronal and glial glutamate transporters (EAATs, a family of excitatory amino acid transporters) is critical for shaping synaptic responses and for preventing excitotoxicity. Two of these transporters, EAAT4 in Purkinje neurons (PN) and EAAT1 in Bergmann gli...

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Detalles Bibliográficos
Autores principales: Power, Emmet M, Empson, Ruth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549135/
https://www.ncbi.nlm.nih.gov/pubmed/26331027
http://dx.doi.org/10.1186/2053-8871-1-3