Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4

BACKGROUND: Recent studies have shown that microRNA-29 (miR-29) is significantly decreased in liver fibrosis and that its downregulation influences the activation of hepatic stellate cells (HSCs). In addition, inhibition of the activity of histone deacetylases 4 (HDAC4) has been shown to strongly re...

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Detalles Bibliográficos
Autores principales: Huang, Ying-Hsien, Tiao, Mao-Meng, Huang, Li-Tung, Chuang, Jiin-Haur, Kuo, Kuang-Che, Yang, Ya-Ling, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549141/
https://www.ncbi.nlm.nih.gov/pubmed/26305546
http://dx.doi.org/10.1371/journal.pone.0136453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549141/
https://www.ncbi.nlm.nih.gov/pubmed/26305546
http://dx.doi.org/10.1371/journal.pone.0136453

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