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iTRAQ Quantitative Proteomic Comparison of Metastatic and Non-Metastatic Uveal Melanoma Tumors

BACKGROUND: Uveal melanoma is the most common malignancy of the adult eye. The overall mortality rate is high because this aggressive cancer often metastasizes before ophthalmic diagnosis. Quantitative proteomic analysis of primary metastasizing and non-metastasizing tumors was pursued for insights...

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Detalles Bibliográficos
Autores principales: Crabb, John W., Hu, Bo, Crabb, John S., Triozzi, Pierre, Saunthararajah, Yogen, Tubbs, Raymond, Singh, Arun D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549237/
https://www.ncbi.nlm.nih.gov/pubmed/26305875
http://dx.doi.org/10.1371/journal.pone.0135543